TACTICS OF TREATMENT OF BENIGN PROSTATIC HYPERPLASIA AT THE STAGE OF DECOMPENSATION

Shormanov Igor' Sergeevich, Doctor of medical sciences, associate professor, head of sub-department of urology with nephrology, Yaroslavl Medical University (5 Revolutsionnaya street, Yaroslavl, Russia), i-s-shormanov@yandex.ru
Shormanov Sergey Venediktovich, Doctor of medical sciences, professor, sub-department of pathological anatomy, Yaroslavl Medical University (5 Revolutsionnaya street, Yaroslavl, Russia), s_v_shormanov@mail.ru
Ukharskiy Andrey Vyacheslavovich, Assistant, sub-department of urology with nephrology, Yaroslavl Medical
University (5 Revolutsionnaya street, Yaroslavl, Russia), 8229990@gmail.ru
Solov'ev Andrey Sergeevich, Senior laboratory assistant, sub-department of urology with nephrology, Yaroslavl Medical University (5 Revolutsionnaya street, Yaroslavl, Russia), andrey14_09@mail.ru

616.65-007.61-089

10.21685/2072-3032-2016-2-7

Background. The aim of the article is to study the influence of hyperbaric oxy-genation (HBO) in patients with BPH at the stage of decompensation.
Materials and methods. The study was carried out among 103 patients with BPH at the stage of decompensation. As the first stage of treatment of BPH all patients underwent cystostomy. The patients were divided into two groups. The patients of the control group after cystostomy received standard therapy. In the study group the patients on the first day after cystostomy additionally received 10 sessions of HBOT. Further, in a period of 30 to 45 days after cystostomy, all patients underwent TURP.
Results. Laboratory signs of prostatitis were diagnosed in 68.8 per cent of the ex-amined patients. 30 days after cystostomy, prostatitis was diagnosed in 40.8 percent in the control group and 16.7 % in the study group. The patients of the studied groups 10 days after the cystostomy had the blood urea level 35.1 % lower, and GFR - 34.8 % higher than in the control group. 15 days after TURP the researchers observed the best functional state of the bladder in patients treated with HBO, which was reflected by an increase of Qmax by 26 %, reduction of the number of points on the IPSS scale by 31 %, and reduction of residual urine two times in comparison with the control group. 6 months after TURP, the difference of IPSS/QoL between the study and control groups was 20.3/27,6 %, respectively.
Conclusion. The study showed a positive influence of hyperbaric oxygenation on the functional state of kidneys and bladder, the severity of infectious-inflammatory complications of BPH, as well as immediate and long-term results of radical surgical treatment.

hyperbaric oxygenation, benign prostatic hyperplasia, BPH, transurethral resection of the prostate, TUR of BPH and chronic urinary retention, epitcystostomy.

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